people
|Faculty
|Nathaniel Rosi
 |
Nathaniel Rosi Department of Chemistry |
We focus on developing strategies for the design and synthesis of new materials having broad potential applications in areas such as catalysis, sensing, and drug delivery. To accomplish our goals, we employ an approach that involves the rational assembly of chemical building blocks (e.g. small molecules, biomolecules, metal clusters, or nanostructures) into well-ordered hierarchical structures. Ultimately, we strive toward the conception and realization of unifying design principles that will facilitate the organization of such building blocks over multiple length scales.
Given the multi-disciplinary nature of our research, students and postdocs from diverse chemical disciplines are encouraged to participate. While in lab, they become familiar with a wide array of solution, solid-state, automated, and high-throughput synthetic methods. Further, they become skilled at using NMR, mass spectroscopy, IR, SEM, TEM, thermal analysis, sorption, fluorescence spectroscopy and microscopy, and X-ray diffraction methods to characterize their materials. They are encouraged to attend national and international meetings to disseminate their most exciting results.
Awards
Outstanding Graduate Student Research Award, University of Michigan, 2001; Rackham Travel/International Institute Travel Grant, University of Michigan, 2001 and 2002
Selected Publications
"Asymmetric Functionalization of Gold Nanoparticles with Oligonucleotides," X. Xu, N.L. Rosi, Y. Wang, F. Huo, and C.A. Mirkin, J. Am. Chem. Soc, 2006, 128, 9286-9287
"Oligonucleotide-Modified Gold Nanoparticles for Intracellular Gene Regulation," N.L. Rosi*, D.A. Giljohann*, C.S. Thaxton, A.K.R. Lytton-Jean, M.S. Han, and C.A. Mirkin, Science, 2006, 312, 1027-1030
"Metal-Organic Frameworks Constructed from Rod-Shaped Secondary Building Units," N.L. Rosi, J. Kim, M. Eddaoudi, B. Chen, M. O’Keeffe, and O.M. Yaghi, J. Am. Chem. Soc., 2005, 127, 1504-1518
"Nanostructures in Biodiagnostics," N.L. Rosi and C.A. Mirkin, Chem. Rev., 2005, 105, 1547-1562
"Sacrificial Biotemplates for the formation of Nanostructured Metallic Microshells," E.K. Payne*, N.L. Rosi*, C. Xue, and C.A. Mirkin, Angew. Chem. Int. Ed., 2005, 44, 5064-5067
"Control of Nanoparticle Assembly Using DNA-Modified Diatom Templates," N.L. Rosi, C.S. Thaxton, and C. A. Mirkin, Angew. Chem. Int. Ed., 2004, 43, 5500-5503
"Hydrogen Storage in Microporous Metal-Organic Frameworks," N.L. Rosi, J. Eckert, M. Eddaoudi, D.T. Vodak, J. Kim, M. O’Keeffe, and O.M. Yaghi, Science, 2003, 300, 1127-1129
"Infinite Secondary Building Units and Forbidden Catenation in Metal-Organic Frameworks," N.L. Rosi, M. Eddaoudi, J. Kim, M. O’Keeffe, and O.M. Yaghi, Angew. Chem. Int. Ed., 2002, 41, 284-287
"Systematic Design of Pore Size and Functionality in Isoreticular Metal-Organic Frameworks," M. Eddaoudi, J. Kim, N.L. Rosi, D. Vodak, J. Wachter, M. O’Keeffe, and O.M. Yaghi, Science, 2002, 295, 468-472
"Advances in the Chemistry of Metal-Organic Frameworks," N.L. Rosi, M. Eddaoudi, J. Kim, M. O’Keeffe, and O.M. Yaghi, CrystEngComm, 2002, 4, 401-404
